Oxiracetam: Benefits, Uses, Dosage, and Side Effects

A potent stimulant nootropic in the racetam family known for boosting memory, learning, and concentration.

Oxiracetam: Benefits, Uses, Dosage, and Side Effects

Whether you are looking for immediate stimulant properties and energy or long-term improvement in memory and cognitive function, oxiracetam is a solid choice.

Despite being newer than some other members of the racetam class, substantial research shows the many benefits of oxiracetam.

Some unique properties differentiate oxiracetam from related nootropics. Because of this, it acts differently in terms of results, but what exactly is oxiracetam, and why should you be interested in its use as a beneficial nootropic substance?

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    What is Oxiracetam?

    The racetam drugs were developed to find an effective treatment option for memory loss and age-related cognitive decline. Oxiracetam is a synthetic derivative of piracetam and was developed in the 1970s under the code ISF 2522.

    Oxiracetam is more effective than piracetam, which is one of the primary reasons that its use still continues today.

    It acts as a mild stimulant that can improve focus and boost users’ energy levels. Clinical trials show that it may even be helpful in the treatment of Alzheimer’s disease.

    In addition, oxiracetam is commonly used worldwide as a potent nootropic supplement for improving memory, learning, and overall cognitive function.

    How Does Oxiracetam Work In The Brain?

    There are several mechanisms of action behind the benefits that are associated with oxiracetam. Possibly the most important mechanism is the way it modulates the release of the neurotransmitters acetylcholine and glutamate, as it impacts the cholinergic and glutamatergic systems.

    Furthermore, oxiracetam enhances the communication between neurons in the hippocampus, which regulated memory, emotion, and other aspects of the central nervous system.

    These mechanisms help to provide improved memory, motivation, and other aspects of cognition.

    Finally, oxiracetam is an ampakine that can act as a stimulant drug in some instances and can impact the affinity of AMPA receptors. It may even stimulate the production of cellular energy and prevent premature cell death in neurons.

    What Are The Benefits of Oxiracetam?

    Oxiracetam offers a lot of benefits as a nootropic with tons of potential. This is the reason that it remains popular as a sole supplement or when added to nootropic stacks.

    Improves Memory

    The enhancement of memory is probably the most well-known use of oxiracetam. There are plenty of animal studies and human clinical trials that show the extent of this benefit.

    Not only can it improve general remembrance ability, but it may also improve memory formation and retention (1).

    Evidence suggests that oxiracetam could aid with the speed of information recall and an increase in alertness that can contribute to better recollection. A review of the science behind these effects shows that oxiracetam could be good for long and short-term memory and reasoning.

    People who use oxiracetam often find that they can finally recall memories that they had been lost for years. In addition, the boost in memory formation could help to provide a clearer mental memory moving forward. Additionally, the cognitive enhancement effects could increase these beneficial features.

    However, it is essential to note that the research on oxiracetam is primarily on participants who suffer from Alzheimer’s disease and other forms of dementia.

    Still, the evidence is promising, and many researchers believe it can boost the functioning of memories in people without cognitive impairment.

    Enhances Learning

    There is substantial research oxiracetam may help with learning and memory. Part of this is likely only because of the impact on recollection itself, but it also appears that it may also boost learning capacity (2).

    The improvement of learning ability is likely a combination of the gain on information processing and the boost to memory formation. Furthermore, oxiracetam may eliminate mental fatigue and improve analytical thinking because it is a mild stimulant.

    Not only does it impact learning activity, but it also speeds up the ability to consume information because of the mild stimulant properties and cognitive enhancement. This means that you can digest and process more materials in a similar time frame.

    Students often use oxiracetam as a study drug. Still, it can also be beneficial for completing office work that requires you to retain learned materials while simultaneously remaining productive throughout the workday.

    Thus, not only can you speed up your learning ability, but you will also be able to recollect the things you learned quickly.

    Improves Verbal Fluency

    Public speakers often choose oxiracetam over other nootropic racetams because of its ability to improve verbal fluency.

    This is related to the impact on cognition because verbal fluency requires the ability to access things from the human brain to convert into speaking and sentence forming (3).

    Not only does oxiracetam help patients with dementia formulate their thoughts and structure their words, but the science shows evidence that it could be beneficial for adults in otherwise good health. The CNS stimulation may also reduce brain fog so the thoughts can be easily converted into verbiage.

    The combination of the positive impact on verbal fluency and the effect on learning causes a boost to the ability to learn from the spoken word that is always an important factor in communication skills.

    This could potentially help with performance on the job and in personal relationships.

    Many people with social anxiety turn to oxiracetam to ease their inhibitions as well. If you often find yourself unable to form adequate sentences or communicate effectively, these effects may benefit your well-being.

    Boosts Concentration and Focus

    Oxiracetam functions using many mechanisms as a brain booster, which can improve concentration and focus. This can be great for the completion of long, mundane tasks or help as a study aid.

    In addition, you make the most out of that concentration because of the effects on cognitive function (4).

    Since oxiracetam is a mild stimulant, it can help make the most tedious tasks and work seem interesting and allow users to concentrate adequately.

    This makes it a potential enhancer of mental performance that could increase productivity and the quality of work. In addition, studies show that human subjects can benefit from using a mild stimulant, like oxiracetam, combined with more traditional nootropic drugs.

    Many experts are interested in the effectiveness of these stimulant properties for the treatment of ADHD. The processes that make prolonged focus achievable could offer a beneficial result without the cost and side effects associated with ADHD drugs.

    Finally, besides making it easier to focus on something for a prolonged period, it can also boost energy levels. This allows for more productivity and work without becoming tired or distracted.

    Therefore, these findings of effects could offer a variety of purposes as a study drug or a nootropic to take before work or exercise.

    Has Neuro-Protective Effects

    Oxiracetam also offers fantastic neuroprotective effects for overall brain health.

    Animal studies show it may be a potential treatment for brain damage caused by the death of brain cells, Alzheimer’s disease, multi-infarct dementia, blood-brain barrier dysfunction, and brain trauma caused by neurotoxins (5).

    According to human studies, some of the effects of oxiracetam on brain health could prevent cognitive decline and boost cognition in older people.

    In addition, some of the studies and clinical trials show that oxiracetam supplementation may help with cognitive impairment caused by low brain oxygen levels.

    Furthermore, one clinical trial on stroke patients with high blood pressure found that the patients who combined oxiracetam with nerve growth factor (NGF) had better recovery.

    Also, there is evidence that the elderly or those who experience age-related decline could improve accuracy, attention, and retention more than those who did not supplement with a racetam nootropic.

    Oxiracetam has other neuroprotective features and can reduce inflammation and blood flow that could impact the human body and mind. Studies show that this can protect against brain damage and that the increase in blood flow in the brain could also be beneficial for healthy adults (6).

    Helps To Stay Awake and Alert

    Oxiracetam is possibly the best member of the racetam family for promoting wakefulness because of the stimulant effect it has on the mind. Research even shows that patients who use oxiracetam may have increased alertness than those who take other racetams or nootropics.

    The energy and wakefulness that it promotes are not overstimulated but offer subtle effects that could provide potential as a beneficial alternative to other stimulants and related drugs.

    The impact on the neurotransmitter acetylcholine balances out the energy so that the usage is natural and the experience is comfortable.

    There is even research that shows that this supplement may be suitable for boosting energy metabolism. This could make it a good option for those trying to maintain healthy body weight without the side effects common with diet supplements.

    Finally, since the energy that oxiracetam may provide is more natural and subtle, it has less of a tendency to interrupt sleep cycles. Thus, while some people still have interrupted sleep patterns, the impacts are less severe without peak levels of stimulation followed by severe crashes in energy.

    How To Take Oxiracetam?

    Suppose you are planning on taking oxiracetam for its beneficial effects. In that case, you surely want to know the proper dosages, how long it lasts, and potential stacks that could offer improved outcomes.


    Oxiracetam typically comes in either capsule or powder form, but it is also water-soluble to be mixed into a beverage for convenience. While the effective dose will range depending on the users and the desired effects, some guidelines can help you find the sweet spot.

    The recommendation is to start with a lower dose and then gradually increase until you achieve the dosage for the effects you want.

    A starting dose would be 200 to 400 mg of oxiracetam one to two times per day. Then, you can increase to a standard dose of 700 to 800 mg two to three times daily.

    You should also give at least three hours between doses and start the day with the largest dose if you are not dividing them up evenly.

    What Is The Half-life?

    The half-life of oxiracetam is between 8 and 10 hours. However, the effects are only experienced for around 4 hours after consumption. Also, it is unlikely to take effect an hour after taking the compound.

    The half-life also means that the overall effect of these supplements will be best when it is taken every day. Also, nootropics and other cognitive compounds often work best when you cycle them.

    For oxiracetam, we suggest cycling it 5 days on, 2 days off. You can also try three weeks on, 1 week off if you prefer. Doing this will lead to a better result on the health and cognitive support.

    Oxiracetam Stacks

    It can be highly beneficial to stack this supplement with other nootropics. Let’s look at some of the more popular ways to stack oxiracetam.

    Oxiracetam and Choline Stack

    The nootropic effect will be more remarkable when you stack this compound with a good choline source, particularly with energetic feelings of focus and balanced results.

    Using a choline stack not only increases the effect but also maintains the experience without uncomfortable symptoms.

    Generally, doses are best consumed together 1 to 2 times per day. The recommended doses are 300 mg Alpha-GPC and 750 mg oxiracetam.

    Oxiracetam and Noopept Stack

    Adding Noopept to your stack can be a great way to boost most of the effects.

    This is a combination preferred for those who want a great boost in mood, along with an increase in performance and better neuroprotective features.

    With this combination, you want to be careful not to overstimulate the cholinergic system.

    Therefore, it is best to start with a low dose like 12 mg Noopept with 400 mg oxiracetam, and you can take them one or two times per day.

    Oxiracetam and Aniracetam Stack

    Students and athletes like an aniracetam stack because both nootropics are ampakines.

    This means that the stimulant effects and increase in cognitive abilities will be increased and enhanced. It is also an excellent choice for boosting mood and reducing anxiety.

    The recommended doses are 750 mg of both oxiracetam and aniracetam. You can also take these doses one or two times per day.

    Does Oxiracetam Have Side Effects?

    This compound is considered safe for healthy people, but there are some side effects as with any drug. If you develop a side effect, reduce your dose, or consult with a doctor for support in severe circumstances.

    According to clinical trials and research, the most common side effects are nausea, headaches, hypertension, constipation, diarrhea, and overexcitability.

    Some people also find that they have trouble sleeping, especially when the substance is taken later in the day or with other stimulants, even caffeine.

    You should avoid taking stimulant nootropics if you recently suffered from a stroke or if you are on drugs for epilepsy. In addition, it is best to be careful if you suffer from hypertension, migraine headaches, or restlessness.

    Where To Buy Oxiracetam?

    While you can buy oxiracetam from almost any website that sells nootropics, they can vary significantly in quality.

    Therefore, it is best to ensure that you purchase nootropics from trusted sources because it can make a difference in both side effects and benefits. It is also wise to be wary of websites that make outrageous claims.

    From our experience, to make a reliable purchase, we recommend buying oxiracetam from PureRawz. The company delivers a high-quality compound that complies with purity and safety benchmarks.


    Oxiracetam is a fantastic nootropic option that has proven benefits based on research studies. It is a brilliant choice if you want a clean, subtle form of natural mood-boosting and energetic effects.

    In addition, it can improve cognitive ability in numerous ways and enhance mental functions like focus, recollection, and brain health.

    Best Oxiracetam choice

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